Cck-1 receptor modulators

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 231/12 (2006.01) A61K 31/415 (2006.01) A61K 31/4155 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 403/04 (2006.01) C07D 403/06 (2006.01) C07D 403/12 (2006.01) C07D 405/04 (2006.01) C07D 405/06 (2006.01) C07D 405/10 (2006.01) C07D 405/14 (2006.01) C07D 409/06 (2006.01)

Patent

CA 2530737

There are provided by the present invention certain pyrazole based CCK-1 receptor modulators which have the general formula: (I) wherein Ar is an aromatic or heteroaromatic group, X is a hydrocarbon linker, Y is a bond or hydrocarbon linker and R1, R2, R3, R4 and R5 are certain organic substituents, and methods of making the same.

La présente invention concerne certains modulateurs du récepteur de CCK-1 à base de pyrazole ayant la formule générale (I) où Ar représente un groupe aromatique ou hétéroaromatique, X représente un lieur d'hydrocarbure, Y représente une liaison ou un lieur d'hydrocarbure et R?1¿, R?2¿, R?3¿, R?4¿ et R?5¿ représentent certains substituants organiques. L'invention concerne également leurs procédés de production.

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