C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
167/240, 530/5.0
C07K 5/06 (2006.01) C07K 5/078 (2006.01) C07K 5/097 (2006.01) A61K 38/00 (2006.01)
Patent
CA 1326108
Abstract of the Disclosure In one aspect, cholecystokinin (CCK) antagonists of the formula: Image or a pharmaceutically acceptable salt thereof, wherein each R1 is, independently, an alkyl group having 1-5, inclusive, carbon atoms. an alkoxy group having 1-5, inclusive, carbon atoms, a halogen, amino, hydroxy, nitro, cyano, carboxyl, trifluoreomethyl, ethyl carboxylate, or a hydrogen; m is an integer between 0 and 2, inclusive,; and A is either Image , where n is an integer between 1 and 5, inclusive, and R2 is hydroxy, an alkoxy group having 1-5, inclusive, carbon atoms, aralkoxy, aralkyl, amino, an alkyl group having 1-5, inclusive, carbon atoms, an alkylamino group having 1-5, inclusive, carbon atoms, a dialkylamino group with each alkyl group, independently having 1-5, inclusive, carbon atoms, a cycloalkylamino group wherein the ring has 4-6, inclusive, carbon atoms, or morpholino; or A is an alkyl group having 1-5, inclusive, carbon atoms, a hydroxyalkyl group having 1-5, inclusive, carbon atoms, an alkoxyalkyl group having 2-8, inclusive, carbon atoms, an aralkoxyalkyl having 8-14, inclusive, carbon atoms, an aryl group having 6-14, inclusive, carbon atoms, an aralkyl group having 6-14, inclusive, carbon atoms, and a cycloalkyl group having 3-12, inclusive, carbon atoms.
596292
Biomeasure Inc.
Smart & Biggar
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