Ccr1 antagonists for the treatment of i.a. demyelinating...

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 491/04 (2006.01) C07D 221/00 (2006.01) C07D 313/00 (2006.01)

Patent

CA 2505874

The invention provides compounds having the formula (I): wherein R1 is halogen. The invention also provides compositions comprising the compounds, and methods of treating diseases or disorders that comprise administering one or more of the compounds to a subject in need thereof. The disclosed compounds have CCR1 antagonist activity.

L'invention a trait à des composés représentés par la formule (I), dans laquelle R?1¿ représente halogène. L'invention concerne également des compositions contenant lesdits composés, et des méthodes destinées à traiter des maladies ou des troubles, qui consistent à administrer un ou plusieurs desdits composés à un sujet. Les composés selon l'invention présentent une activité antagoniste de CCR1.

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