Cct6s as modifiers of the rb pathway and methods of use

Details Cct6s as modifiers of the rb pathway and methods of use Cct6s as modifiers of the rb pathway and methods of use

C - Chemistry, Metallurgy

12

Q

C12Q 1/00 (2006.01) A01N 61/00 (2006.01) C12N 1/00 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/48 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2506686

Human CCT6 genes are identified as modulators of the RB pathway, and thus are therapeutic targets for disorders associated with defective RB function. Methods for identifying modulators of RB, comprising screening for agents that modulate the activity of CCT6 are provided.

Des gènes CCT6 humains sont identifiés comme modulateurs de la voie RB et sont, en conséquence, des cibles thérapeutiques pour des troubles associés à une fonction RB défectueuse. L'invention concerne des procédés d'identification de modulateurs de RB, comprenant la sélection d'agents modulant l'activité de CCT6.

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