A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 35/14 (2006.01) A61P 37/06 (2006.01) C12Q 1/02 (2006.01) C12Q 1/04 (2006.01) G01N 33/567 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)
Patent
CA 2655392
The invention provides methods of isolating CD127lo/- immunosuppressive regulatory T cells which can be greatly enriched for FoxP3, methods of expanding the isolated cells, pharmaceutical compositions of such cells, and methods of their use in the treatment of autoimmune and other immune system mediated disorders.
L'invention concerne des procédés d'isolement des lymphocytes T régulateurs immunosuppresseurs CD127lo/- qui peuvent être fortement enrichis en ce qui concerne FoxP3, des procédés d'expansion des cellules isolées, des compositions pharmaceutiques desdites cellules, et des procédés d'utilisation correspondants pour le traitement de maladies auto-immunes et d'autres troubles induits par le système immunitaire.
Bluestone Jeffrey A.
Liu Weihong
Putnam Amy
Fetherstonhaugh & Co.
The Regents Of The University Of California
LandOfFree
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