Cd16a binding proteins and use for the treatment of immune...

Details Cd16a binding proteins and use for the treatment of immune... Cd16a binding proteins and use for the treatment of immune...

A - Human Necessities

61

K

A61K 39/395 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2487932

CD16A binding proteins useful for the reduction of a deleterious immune response are described. In one aspect, humanized anti-CD16A antibodies, optionally lacking effector function, are used for treatment of immune disorders such as idiopathic thrombocytopenic purpura and autoimmune hemolytic anemia.

L'invention concerne des protéines de liaison à CD16A, utiles pour diminuer une réponse immunitaire délétère. Dans un aspect, des anticorps anti-CD16A, éventuellement dépourvus de fonction effectrice, sont utilisés pour le traitement de troubles immunitaires, tels que le purpura thrombocytopénique idiopathique ou l'anémie hémolytique autoimmune.

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