Cd18 peptide medicaments for the treatment of disease

Details Cd18 peptide medicaments for the treatment of disease Cd18 peptide medicaments for the treatment of disease

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) C07K 14/705 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2090427

2090427 9203473 PCTABS00010 Peptide medicaments, and antibody thereto, useful for treating or preventing diseases, particularly diseases involving an inflammatory response by a host organism against infection, that are preferably derived from the .beta. subunit, CD18, of the leukocyte integrins, and that have the property of either interfering with, or preventing undesirable leukocyte adhesion to biological materials, particular to endothelial cells, or that interfere with, or prevent the chemotaxis of leukocytes through the endothelial cells monolayer, consequently minimizing undesirable cell/tissue leukocyte binding and thus preventing or minimizing diseases resulting therefrom.

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