Cd4 specific recombinant antibody

Details Cd4 specific recombinant antibody Cd4 specific recombinant antibody

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 39/395 (2006.01) C07K 16/18 (2006.01) C07K 16/24 (2006.01) C07K 16/28 (2006.01) C07K 16/46 (2006.01) C07K 19/00 (2006.01) C12N 15/62 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2046904

There are disclosed: a CDR-grafted antibody having at least one chain wherein the framework regions are predominantly derived from a first antibody (acceptor) and at least one CDR is derived from a second antibody (donor), the CDR-grafted antib- ody being capable of binding to the CD4 antigen; processes for its production; nucleotide sequences for use in its production; compositions containing it; and its use in therapy.

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