Cd40 antagonists for use in treating psoriasis and other...

A - Human Necessities – 61 – K

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A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 17/06 (2006.01) A61P 37/06 (2006.01) C07K 16/28 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2406961

A method of treating psoriasis and other inflammatory conditions of the skin by administering anti-CD40 molecules, such as mAb 5D12, in an amount sufficient to inhibit the immunological activation of keratinocytes. The anti- CD40 molecules include antibodies, peptides, and other molecules.

L'invention concerne une méthode de traitement du psoriasis et d'autres inflammations cutanées par administration de molécules anti-CD40, telles que mAb 5D12, en quantité suffisante pour inhiber l'activation immunologique des kératinocytes. Ces molécules anti-CD40 comprennent des anticorps, des peptides ainsi que d'autres molécules.

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