Cd40 antibody formulation and methods

Details Cd40 antibody formulation and methods Cd40 antibody formulation and methods

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61K 31/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2549652

The present invention provides a method of treating tumor in a patient comprising administering to said patient a CD40 agonist antibody according to an intermittent dosing schedule. The present invention also provides a method of treating tumor in a patient comprising administering a combination of a CD40 agonist antibody and a DNA replication inhibitor. Also provided is a formulation for use in the treatment.

Selon cette méthode de traitement de tumeurs chez un patient, on administre au patient un anticorps agoniste de CD40 selon un plan d'administration intermittente. L'invention concerne également une méthode de traitement de tumeurs chez un patient qui comprend l'administration d'une combinaison d'un anticorps agoniste de CD40 et d'un inhibiteur de la réplication de l'ADN, ainsi qu'une formulation utilisée dans le traitement.

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