Cd6 ligand

Details Cd6 ligand Cd6 ligand

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/16 (2006.01) C07K 14/435 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) G01N 33/567 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2175247

The present invention relates, in general, to CD6 and, in particular, to a CD6 ligand present on the surface of thymic epithelial cells, monocytes, activated T cells and a variety of other cell types. The invention further relates to methods of inhibiting the interaction of CD6 and the CD6 ligand, and to methods of screening compounds for then ability to inhibit that interaction.

CD6 et en particulier ligand pour CD6 présent sur la surface de cellules épithéliales thymiques, de monocytes, de lymphocytes T activés et d'une série d'autres types de cellules. La présente invention concerne en outre des procédés permettant d'inhiber l'interaction de CD6 et du ligand pour CD6, ainsi que des procédés de criblage de composés capables d'inhiber ladite interaction.

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