C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/0784 (2010.01) A61K 35/14 (2006.01) A61K 38/20 (2006.01) A61K 38/21 (2006.01) A61P 31/12 (2006.01) A61P 37/02 (2006.01) A61K 35/12 (2006.01)
Patent
CA 2442300
Lymphoid dendritic cells with an immunophenotype of CD8.alpha. + can be produced by a method which comprises culturing human hematopoietic stem cells in a medium containing GM-CSF, followed by culturing in a medium containing IFN-.UPSILON., said cells being useful in various immunotherapies.
La présente invention concerne un procédé de production de cellules dendritiques lymphoïdes comprenant un immunophénotype de CD8.alpha. +. Ce procédé consiste à cultiver des cellules souches hématopoïétiques humaines dans un milieu contenant GM-CSF, puis à les cultiver dans un milieu contenant IFN-.UPSILON.. Ces cellules sont utiles dans de nombreuses immunothérapies.
Kim Hugh Chul
Kim Hyun-Soo
Lee Kyung Bock
Cassan Maclean
Kim Hugh-Chul
Kim Hyun-Soo
Lifecord Inc.
Pharmicell Co. Ltd.
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