Cd8 as an inhibitor of the cellular immune system

Details Cd8 as an inhibitor of the cellular immune system Cd8 as an inhibitor of the cellular immune system

A - Human Necessities

61

K

A61K 38/17 (2006.01) C07K 14/705 (2006.01) C12N 15/12 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2308463

A method for inhibiting CTL activity is described in which soluble CD8 is used as the inhibitor. The method is particularly useful for immunosuppressive therapy in which inhibition of CTL activity is desirable, for example in patients undergoing transplantation.

L'invention porte sur un procédé d'inhibition de l'activité de la cellule CTL utilisant comme inhibiteur une molécule CD8 soluble. Ledit procédé s'avère particulièrement utile dans les thérapies immuno-suppressives où l'inhibition de l'activité des CTL est désirable, par exemple chez des patients subissant une transplantation.

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