C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/48 (2006.01) A61K 31/505 (2006.01) A61K 31/506 (2006.01) A61P 35/00 (2006.01) C07D 239/34 (2006.01) C07D 239/42 (2006.01) C07D 239/46 (2006.01) C07D 239/47 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 403/04 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/14 (2006.01) C07D 417/12 (2006.01) C07D 495/10 (2006.01) C07D 521/00 (2006.01) C07F 9/6512 (2006.01)
Patent
CA 2449118
The invention relates to the pyrimidine derivatives of general formula (1), wherein R1, R2, X, A and B are defined as in the description, for use as inhibitors of the cyclin-dependent kinase. The invention further relates to the production thereof as well as to their use as medicament in the treatment of various diseases.
La présente invention concerne des dérivés de la pyrimidine de formule générale (1) dans laquelle R?1¿, R?2¿, X, A et B sont tels que définis dans la description, lesdits dérivés servant d'inhibiteurs de la kinase dépendante des cyclines (CDK). L'invention se rapporte en outre à leur production ainsi qu'à leur utilisation comme médicament destiné à traiter différentes maladies.
Brumby Thomas
Huwe Christoph
Jautelat Rolf
Luecking Ulrich
Prien Olaf
Bayer Schering Pharma Aktiengesellschaft
Marks & Clerk
Schering Aktiengesellschaft
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