Cdk9 as modifier of the igf pathway and methods of use

Details Cdk9 as modifier of the igf pathway and methods of use Cdk9 as modifier of the igf pathway and methods of use

G - Physics

01

N

G01N 33/53 (2006.01) C07H 21/04 (2006.01) C12N 9/12 (2006.01) C12Q 1/48 (2006.01)

Patent

CA 2568012

Human CDK9 genes are identified as modulators of the IGF pathway, and thus are therapeutic targets for disorders associated with defective IGF function. Methods for identifying modulators of IGF, comprising screening for agents that modulate the activity of CDK9 are provided.

On a identifié des gènes CDK9 humains comme étant des modulateurs de la voie IGF et, ils sont par conséquent des cibles thérapeutiques pour des troubles associés et à une fonction IGF défaillante. Cette invention concerne aussi des techniques d'identification de modulateurs de IGF, comprenant une recherche d'agents qui modulent l'activité de CDK9.

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