Cdna sequence of dengue virus serotype 1 (singapore strain)

Details Cdna sequence of dengue virus serotype 1 (singapore strain) Cdna sequence of dengue virus serotype 1 (singapore strain)

C - Chemistry, Metallurgy

12

N

C12N 15/40 (2006.01) A61K 39/12 (2006.01) A61K 39/42 (2006.01) C07K 14/18 (2006.01) C07K 19/00 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 7/00 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2134666

2134666 9322440 PCTABS00027 DEN1-S275/90 (ECACC V92042111) is a new strain of Dengue virus serotype 1. The complete cDNA sequence of this virus has been cloned and protein-coding fragments thereof have been used in the construction of expression plasmids. DEN1-S275/90 in inactivated form, DEN1-S275/90 polypeptides or fusion proteins thereof can be incorporated into vaccines for immunisation against DEN1-S275/90 and other DEN1 viruses. The invention further provides diagnostic reagents e.g. labelled antibodies to DEN1-S275/90 proteins, and kits to detect DEN1 virus.

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