Cdr-repaired antibodies

Details Cdr-repaired antibodies Cdr-repaired antibodies

C - Chemistry, Metallurgy

07

K

C07K 16/46 (2006.01) C12N 15/10 (2006.01)

Patent

CA 2555820

The present application concerns restoring antigen binding during humanization of antibodies through the selection of repaired hypervariable regions rather than through framework changes.

La présente invention a trait à la restauration de la liaison à l'antigène lors de l'humanisation d'anticorps par la sélection de régions hypervariables réparées au lieu de modifications de cadre.

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