Cecropin-like polypeptides with activity against...

Details Cecropin-like polypeptides with activity against... Cecropin-like polypeptides with activity against...

C - Chemistry, Metallurgy

12

N

167/103, 530/7.1

C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/435 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1340841

The invention relates to cecropin-like polypeptides with a variety of C-terminus modifications. Conversion of the terminal carboxy group to a homoserine extended neutral, negatively charged or positively charged form results in the polypeptides of the invention that have significant bactericidal effects against both Gram-positive and Gram-negative bacteria.

558211

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