C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/54 (2006.01) A61K 31/415 (2006.01) A61P 29/00 (2006.01)
Patent
CA 2505635
N-[[4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]- sulfonyl]propanamide and pharmaceutically acceptable salts thereof are useful prodrugs of the selective COX-2 inhibitory drug celecoxib, which can be administrated to a subject by any suitable route.
L'invention concerne le N-[[4-[5-(4-méthylphényl)-3-(trifluorométhyl)-1H-pyrazole-1-yl]phényl]-sulfonyl]propanamide et ses sels pharmaceutiquement acceptables, utilisés en tant que promédicaments du médicament celecoxib inhibiteur sélectif de la COX-2, qui peut être administré à un sujet par une voie appropriée.
Ewing Gary D.
Graneto Matthew J.
Pharmacia Corporation
Smart & Biggar
LandOfFree
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