C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 323/62 (2006.01) A61K 31/10 (2006.01) A61K 31/33 (2006.01) C07D 207/09 (2006.01) C07D 207/14 (2006.01) C07D 207/20 (2006.01) C07D 207/22 (2006.01) C07D 207/26 (2006.01) C07D 207/27 (2006.01) C07D 209/08 (2006.01) C07D 209/18 (2006.01) C07D 211/22 (2006.01) C07D 211/26 (2006.01) C07D 211/42 (2006.01) C07D 211/46 (2006.01) C07D 211/54 (2006.01) C07D 211/60 (2006.01) C07D 211/62 (2006.01) C07D 211/74 (2006.01) C07D 213/74 (2006.01) C07D 213/75 (2006.01) C07D 213/81 (2006.01) C07D 215/36 (2006.01) C07D 217
Patent
CA 2356320
The present invention relates to novel cinnamide compounds of formula I, (see formula I) with the proviso that at least one of R1 to R3 is a "cis-cinnamide" or a "trans- cinnamide", defined as (see formula II and III) that are useful for treating inflammatory and immune disease, to pharmaceutical compositions containing these compounds, and to methods of inhibiting inflammation or suppressing immune response in a mammal.
Cette invention a trait à de nouveaux composés de cinnamide des plus utiles pour traiter des inflammations et des maladies immunes, à des compositions pharmaceutiques contenant ces composés et à des méthodes permettant d'inhiber une inflammation ou de supprimer une réponse immunitaire chez un mammifère.
Boyd Steven A.
Freeman Jennifer C.
Gunawardana Indrani W.
Jae Hwan-Soo
Link James
Abbott Laboratories
Gowling Lafleur Henderson Llp
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