Cell adhesion inhibitors

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/78 (2006.01) A61K 38/04 (2006.01) A61K 38/39 (2006.01) C07K 5/00 (2006.01) C07K 5/02 (2006.01) C07K 5/06 (2006.01) C07K 5/072 (2006.01) C07K 5/083 (2006.01) C07K 5/09 (2006.01) C07K 5/093 (2006.01) C07K 5/097 (2006.01) C07K 5/103 (2006.01) C07K 5/107 (2006.01) C07K 5/117 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2226868

The present invention relates to novel compounds that are useful for inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies. This invention also relates to pharmaceutical formulations comprising these compounds and methods of using them for inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies. The compounds and pharmaceutical composition of this inveniton can be used as therapeutic or prophylactic agents. They are particularly well-suited for treatment of many inflammatory and autoimmune diseases.

La présente invention concerne des composés nouveaux servant à inhiber et empêcher l'adhérence cellulaire et les pathologies à médiation par adhérence cellulaire. Elle concerne également des formulations pharmaceutiques renfermant ces composés et leur procédés d'utilisation en vue d'empêcher ou de prévenir l'adhérence cellulaire et les pathologies à médiation par adhérence cellulaire. Les composés et les compositions pharmaceutiques qui font l'objet de la présente invention peuvent être utilisés en tant qu'agents thérapeutiques ou prophylactiques. Ils sont particulièrement appropriés pour le traitement de nombreuses maladies inflammatoires et auto-immunes.

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