Cell adhesion resisting surfaces

Details Cell adhesion resisting surfaces Cell adhesion resisting surfaces

C - Chemistry, Metallurgy

07

K

C07K 17/10 (2006.01) B05D 3/00 (2006.01) C08J 7/04 (2006.01) C12N 5/00 (2006.01) H05H 1/00 (2006.01)

Patent

CA 2500421

A coated surface that resists cell adhesion comprising hyaluronic acid directly bound to a plasma-treated polymer surface. A process for producing the coated surface is disclosed as are further modifications of the hyaluronic acid by attaching ligand-binding polypeptides (antibodies or antibody binding proteins).

L'invention concerne une surface enrobée qui résiste à l'adhésion cellulaire et qui comprend de l'acide hyaluronique directement lié à une surface polymère traitée au plasma. L'invention concerne également un procédé permettant de produire ladite surface enrobée ainsi que des modifications de l'acide hyaluronique consistant à fixer sur ladite surface des polypeptides se liant aux ligands (anticorps ou protéines se liant à des anticorps).

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