Cell and enzyme compositions for modulating bile acids,...

Details Cell and enzyme compositions for modulating bile acids,... Cell and enzyme compositions for modulating bile acids,...

C - Chemistry, Metallurgy

12

N

C12N 11/00 (2006.01) A23L 1/30 (2006.01) A61K 9/50 (2006.01) A61K 35/00 (2006.01) A61K 38/46 (2006.01) A61K 38/50 (2006.01) A61K 48/00 (2006.01) A61P 3/06 (2006.01) A61P 35/00 (2006.01) G01N 33/92 (2006.01)

Patent

CA 2517245

The invention relates to immobilized or encapsulated enzyme and/or cells to lower bile acids and cholesterol. The invention also relates to methods of quantitatively measuring bile acids. The invention provides a composition for decreasing the amount of a target compound in the gastrointestinal tract of an animal, comprising: a) a biologically active agent which decreases the amount of the target compound; b) a retainer for retaining the biologically active agent by contacting the agent to limit movement of the agent; and c) a carrier.

L'invention concerne des enzymes et/ou des cellules immobilisées et/ou encapsulées destinées à la réduction d'acides biliaires et de cholestérols. L'invention concerne également des procédés de mesure quantitative d'acides biliaires. L'invention concerne par ailleurs une composition destinée à la réduction de la quantité d'un composé cible dans le tractus gastro-intestinal d'un animal, composée a) d'un agent biologiquement actif réduisant la quantité du composé cible ; b) d'un agent de retenue destiné à retenir l'agent biologiquement actif par contact avec celui-ci ; et, c) d'un porteur.

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