Cell-associated glucosyltransferase, an antibody thereto,...

C - Chemistry – Metallurgy – 12 – N

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C12N 9/10 (2006.01) A61K 6/00 (2006.01) A61K 39/395 (2006.01) A61K 39/40 (2006.01) C07K 16/12 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1325192

Abstract of the Disclosure Cell-associated glucosyltransferase of S. mutans serotypes c, e or f producing dental caries was isolated and purified and its characteristics as an enzyme were revealed. Furthermore, an antibody against said enzyme was prepared from eggs of the hens immunized with said enzyme. Since this antibody effectively prevents adherence of the aforementioned S. mutans to tooth surfaces, it is useful as an effective component for a dental caries prophylactic composition.

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