Cell-based gene therapy in the treatment of pulmonary disorders

A - Human Necessities – 61 – K

Patent

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A61K 38/18 (2006.01) A61K 35/12 (2006.01) A61K 38/44 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2266805

Cell-based gene transfer is effected by administering transfected cells containing an expressible transgene into the pulmonary system of a patient, where the cells express and secrete expression products of the transgene directly into the pulmonary system. Also provided is the use of angiogenic factors in treatment of pulmonary hypertension.

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