G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/483 (2006.01) C12M 1/34 (2006.01)
Patent
CA 2676292
The invention provides a cell co-culture for the selective evaluation of the response of a cell of interest in the co-culture, and methods of using the co-culture. The cell co-culture and the methods are suitable for large-scale / high throughput screening for compounds useful for affecting at least one biological function or event of at least one cell type in the co-culture. The invention further provides kits for using the screening assays.
L'invention concerne une coculture cellulaire pour l'évaluation sélective de la réponse d'une cellule d'intérêt dans la coculture, et des procédés d'utilisation de la coculture. La coculture cellulaire et les procédés sont appropriés pour un criblage à grande échelle/de rendement élevé de composants utiles pour affecter au moins une fonction ou un événement biologique d'au moins un type de cellule dans la coculture. L'invention propose en outre des kits pour utiliser les essais de criblage.
Anderson Kenneth C.
Mcmillin Douglas W.
Mitsiades Constantine S.
Mitsiades Nicholas
Negri Joseph M.
Borden Ladner Gervais Llp
Dana-Farber Cancer Institute Inc.
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