Cell culture products

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A - Human Necessities

61

L

A61L 15/00 (2006.01) A61L 15/24 (2006.01) A61L 15/26 (2006.01) A61L 15/28 (2006.01) A61L 15/32 (2006.01) A61L 15/40 (2006.01) A61L 15/42 (2006.01) C12N 5/00 (2006.01)

Patent

CA 2295163

A wound dressing which comprises a carrier layer having a non-adherent to cell layer on a wound facing surface thereof. The non-adherent layer has bonded thereto a biodegradable cell anchoring layer which anchors mammalian cells. In use, the degradable layer breaks down releasing the cells into the wound site which are discouraged from reattaching to the dressing by the non-adherent layer. Thus the dressing can switch from a cell binding state to a state in which the binding of cells is discouraged. Systems, methods of treatment and methods of manufacturing the dressing are also disclosed.

Cette invention se rapporte à un pansement applicable sur une plaie, qui comporte une couche support dotée d'une couche non adhérente aux cellules sur sa face tournée vers la plaie. Ladite couche non adhérente est soudée à une couche biodégradable d'ancrage à des cellules qui s'ancre à des cellules mammaliennes. En cours d'utilisation, la couche biodégradable se décompose et libère les cellules sur le site de la plaie, la couche non adhérente empêchant lesdites cellules de se fixer ultérieurement au pansement. Ce pansement peut donc passer d'un état de liaison aux cellules à un état dans lequel cette liaison aux cellules est empêchée. L'invention se rapporte en outre à des systèmes, à des méthodes de traitement et à des procédés de fabrication de ce pansement.

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