Cell culturing and storage systems devices and methods

Details Cell culturing and storage systems devices and methods Cell culturing and storage systems devices and methods

C - Chemistry, Metallurgy

12

M

C12M 3/00 (2006.01) C12M 1/22 (2006.01)

Patent

CA 2512008

Featured is a long-term cell culture system (10) being configured and arranged so as to be capable of monitoring the dynamic processes that occur during proliferation and differentiation of stem cells such as central nervous system (CNS) stem cells/embryonic stem cells. In particular aspects, the system allows monitoring of such dynamic processes continually and to focally manipulate the cells by focal application of growth factors such as BMP, CNTF and other growth factors. Preferred systems are capable of electrical recording from the cells.

L'invention concerne un système de culture de cellules à long terme (10) conçu de sorte à permettre la surveillance des processus dynamiques intervenant pendant la prolifération et la différenciation de cellules souches, telles que les cellules souches du système nerveux central (SNC) ou les cellules souches embryonnaires. Selon des aspects particuliers, ce système permet la surveillance continue des processus dynamiques et la manipulation ciblée des cellules par application ciblée de facteurs de croissance, tels que BMP et CNTF, entre autres. Les systèmes préférés permettent de réaliser un enregistrement électrique à partir des cellules.

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