Cell cycle related markers

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01)

Patent

CA 2519307

The present invention relates to pharmacodynamic markers for CDKIs including the candidate 2,6,9-tri-substituted purine known as roscovitine. The identity of these markers facilitates the convenient identification of roscovitine-like activity both in vitro and in vivo.

La présente invention se rapporte à des marqueurs pharmacodynamiques destinés aux inhibiteurs des CDK, qui contiennent la purine 2,6,9-tri-substituée candidate connue sous le nom de roscovitine. L'identité desdits marqueurs facilite l'identification appropriée de l'activité de type roscovitine à la fois in vitro et in vivo.

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