C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2519307
The present invention relates to pharmacodynamic markers for CDKIs including the candidate 2,6,9-tri-substituted purine known as roscovitine. The identity of these markers facilitates the convenient identification of roscovitine-like activity both in vitro and in vivo.
La présente invention se rapporte à des marqueurs pharmacodynamiques destinés aux inhibiteurs des CDK, qui contiennent la purine 2,6,9-tri-substituée candidate connue sous le nom de roscovitine. L'identité desdits marqueurs facilite l'identification appropriée de l'activité de type roscovitine à la fois in vitro et in vivo.
Blake David
Frame Sheelagh
Green Simon R.
Cyclacel Limited
Gowling Lafleur Henderson Llp
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