Cell-delivery agent

Details Cell-delivery agent Cell-delivery agent

C - Chemistry, Metallurgy

07

K

167/129, 167/139

C07K 17/06 (2006.01) A61K 39/395 (2006.01) A61K 41/00 (2006.01)

Patent

CA 1243015

CELL-DELIVERY AGENT Abstract of the Disclosure A photo-cleavable compound for delivery and release of a biologically active substance to selected target cells; the compound includes a binding partner for a specific cell-surface receptor of those target cells, the biologically active substance to be delivered, and a photo-cleavable bridge between the binding partner and the biologically active substance. When the compound is exposed to a heterogeneous population of target and non-target cells, it binds selectively to the receptors on the surface of the target cells. Exposing the compound to light of selected wave length cleaves it, yielding the active substance.

486543

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