Cell division marker

C - Chemistry – Metallurgy – 12 – P

Patent

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Details

C12P 21/06 (2006.01)

Patent

CA 2625078

This application relates to a newly identified animal cell structure, the midbody scar. This structure is a remnant of the midbody that is retained by one daughter cell following cytokinesis and persists through multiple subsequent cell cycles. The midbody scar can be useful as a marker of dividing cells or of a cell's replicative age.

La présente invention se rapporte à une structure nouvellement identifiée des cellules animales, la "cicatrice de la pièce intermédiaire" (midbody scar). Cette structure est un reste de la pièce intermédiaire qui est conservée par l'une des cellules filles après la cytocinèse, et qui subsiste pendant une pluralité de cycles cellulaires subséquents. La cicatrice de la pièce intermédiaire peut servir de marqueur des cellules en mitose, ou de l'âge réplicatif d'une cellule.

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