Cell expansion apparatus with plate bioreactor

C - Chemistry – Metallurgy – 12 – M

Patent

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Details

C12M 3/06 (2006.01)

Patent

CA 2679160

A disposable apparatus for cell expansion, having at least one bioreactor. The bioreactor has a cellular growth area and a supply area, the cellular growth area being adjacent a plate and separated from said supply area by a membrane. The bioreactor comprises a plurality of plates. The plates have a roughened surface or a corrugated surface. At least a sheet of membrane separates adjacent plates. Two sheets between adjacent plates may be separated by a mesh.

La présente invention concerne un appareil jetable pour l'expansion cellulaire, doté d'au moins un bioréacteur. Le bioréacteur présente une surface de croissance cellulaire et une zone d'alimentation, la surface de croissance cellulaire étant adjacente à une plaque et séparée de ladite zone d'alimentation par une membrane. Le bioréacteur comprend une pluralité de plaques. Les plaques présentent une surface rugueuse ou une surface ondulée. Au moins une feuille de membrane sépare les plaques adjacentes. Deux feuilles entre des plaques adjacentes peuvent être séparées par une toile à mailles.

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