Cell growth inhibitory macrocyclic lactones denominated...

Details Cell growth inhibitory macrocyclic lactones denominated... Cell growth inhibitory macrocyclic lactones denominated...

C - Chemistry, Metallurgy

07

D

167/243, 260/350

C07D 321/00 (2006.01) A61K 31/365 (2006.01) C07D 493/04 (2006.01) C07D 493/08 (2006.01)

Patent

CA 2010886

ABSTRACT OF THE DISCLOSURE The isolation and elucidation of novel caffrane macrocyclic lactones denominated "Combretastatin D-l" and "Combretastatin D-2", each of which was found to possess unexpected cell growth inhibitory properties. The lactones have the structural formula: Image wherein: X,X = CH=CH Image

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