C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/10 (2006.01) C07K 14/705 (2006.01) C07K 14/72 (2006.01) C12Q 1/02 (2006.01) C12Q 1/66 (2006.01) G01N 33/15 (2006.01) G01N 33/50 (2006.01) C12N 15/09 (2006.01)
Patent
CA 2413596
Stable muscle cell lines comprising an androgen receptor and methods of using these cells in functional transactivation assays to assess the efficacy of compounds as androgen receptor modulators in a muscle cell background are provided.
L'invention concerne des lignées cellulaires musculaires stables comprenant un récepteur androgène, et des méthodes d'utilisation de ces cellules dans des dosages de transactivation fonctionnelle permettant d'évaluer l'efficacité de composés comme modulateurs de récepteurs androgènes dans un échantillon de contrôle musculaire.
Driscoll Joyce
Lupisella John
Ostrowski Jacek
Salvati Mark
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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