Cell lines and methods for fermentation

C - Chemistry – Metallurgy – 12 – N

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195/134, 195/45,

C12N 15/00 (2006.01) C12N 1/20 (2006.01) C12N 15/52 (2006.01) C12P 1/00 (2006.01) C12P 13/22 (2006.01)

Patent

CA 1236412

Abstract Of The Disclosure Cells which are: 1) capable of converting a raw material to a product compound not produced in the glycolytic pathway via a first bioconver- sion pathway which does not produce a tricarboxylic acid cycle (TAC) inter- mediate; 2) capable of producing a net increase in a TAC intermediate from a first carbon source via a second bioconversion pathway inhibitable by an inhibiting substance produced in the glycolytic pathway; and 3) incapable of producing a net increase in a TAC intermediate other than via the second bio- conversion pathway, are used in a method to produce the product compound.

464797

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