Cell lines expressing cftr and methods of using them

Details Cell lines expressing cftr and methods of using them Cell lines expressing cftr and methods of using them

C - Chemistry, Metallurgy

12

N

C12N 5/10 (2006.01) A61K 31/427 (2006.01) C12N 15/00 (2006.01) C12N 15/67 (2006.01) C12N 15/85 (2006.01) C12Q 1/00 (2006.01) C40B 40/02 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2751215

Disclosed herein are cells and cell lines that stably express CFTR and methods for using those cells and cell lines. The invention also includes techniques for creating these cells and cell lines. The cells and cell lines of this invention are physiologically relevant. They are highly sensitive and provide consistent and reliable results in cell-based assays.

La présente invention concerne des cellules et des lignées cellulaires qui expriment CFTR de façon stable et des procédés d'utilisation de ces cellules et lignées cellulaires. L'invention concerne également des techniques permettant de créer ces cellules et lignées cellulaires. Les cellules et lignées cellulaires de cette invention sont physiologiquement appropriées. Elles sont extrêmement sensibles et donnent des résultats constants et fiables dans les dosages cellulaires.

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