Cell lines for use in the preparation of hybridoma cells

C - Chemistry – Metallurgy – 12 – N

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195/1.101, 195/3

C12N 15/00 (2006.01) C07K 14/52 (2006.01) C07K 14/57 (2006.01) C12N 5/02 (2006.01) C12N 5/16 (2006.01) C12P 21/00 (2006.01)

Patent

CA 1214123

ABSTRACT A novel cell line for use as a parent for hybridoma preparation is provided. This cell line is derived from tumor cells, in particular human tumor cells, other than those originating from bone marrow cells. A method for establishing this cell line is also provided. By fusing this cell line with cells producing useful physiologically active substances, such as B cells immunized with an antigen, a hybridoma capable of active growth can be prepared. This hybridoma can be cultivated for the produc- tion of useful physiologically active substances.

445216

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