Cell or tissue-culturing carrier, and culturing method

Details Cell or tissue-culturing carrier, and culturing method Cell or tissue-culturing carrier, and culturing method

C - Chemistry, Metallurgy

12

N

C12N 5/00 (2006.01) C12N 5/071 (2010.01) C12N 11/08 (2006.01)

Patent

CA 2453539

A support for cell/tissue culture and a method of cell/tissue culture whereby a target tissue or organ can be efficiently regenerated while inhibiting the excessive proliferation of fibroblasts. Using a hydrogel-forming polymer an aqueous solution of which shows heat reversible sol-gel transfer (i.e., occurring as a sol at low temperature and as a gel at high temperature), a cell/tissue culture support wherein fibroblast would not substantially proliferate in the gel due to the hydrogel-forming polymer is constructed.

L'invention concerne un support pour culture de cellules et de tissus et un procédé de culture de cellules et de tissus qui permettent de régénérer efficacement un tissu ou un organe cible tout en inhibant la prolifération excessive de fibroblastes. Au moyen d'un polymère formant un hydrogel dont une solution aqueuse présente un transfert sol-gel thermoréversible (c'est-à-dire, se produisant sous forme de sol à basse température et sous forme de gel à haute température), on construit un support pour culture de cellules et de tissus dans lequel les fibroblastes ne prolifèrent pas dans le gel en raison du polymère formant un hydrogel.

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