Cell penetrating therapeutic agents

Details Cell penetrating therapeutic agents Cell penetrating therapeutic agents

A - Human Necessities

61

K

A61K 47/48 (2006.01)

Patent

CA 2449873

Compositions are provided for delivery of a biologically active agent to a cell, comprising a vehicle having the formula: A - (BC) wherein: A is a lipid- based vehicle; B is a moiety comprising an internalizing peptide; C is a moiety comprising a biologically active agent; (BC) is a complex comprising B and C in which B is conjugated to C; and A is conjugated to (BC).

La présente invention concerne des compositions d'apport d'agent biologiquement actif dans une cellule, qui comprennent un véhicule représenté par la formule: A - (BC). Dans cette formule A est un véhicule à base de lipide, B est une fraction comprenant un peptide d'internalisation, C est une fraction comprenant un agent biologiquement actif, (BC) est un complexe comprenant B et C dans lequel B est conjugué avec C et A est conjugué avec (BC)

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