Cell-permeabilising peptides and polypeptides for microbial...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 7/08 (2006.01) C07K 7/06 (2006.01) C07K 14/00 (2006.01) C07K 19/00 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2700162

The invention encompasses signal peptides and polypeptides comprising these peptides, as well as polynucleotides which encode these peptides or polypeptides. The invention also provides expression vectors comprising these polynucleotides and host cells comprising these vectors. The invention further provides compositions and methods for detecting, targeting, permeabilising, and inhibiting microbial cells, especially methanogen cells, using the disclosed peptides, polypeptides, polynucleotides, expression vectors, or host cells

L'invention concerne des peptides signaux et des polypeptides comprenant ces peptides, ainsi que des polynucléotides codant pour ces peptides ou ces polypeptides. L'invention concerne aussi des vecteurs d'expression comprenant ces polynucléotides et des cellules hôtes comprenant ces vecteurs. L'invention concerne aussi des compositions et des procédés de détection, de ciblage, de perméabilisation et d'inhibition de cellules microbiennes, en particulier des cellules méthanogènes, au moyen des peptides, des polypeptides, des polynucléotides, des vecteurs d'expression ou des cellules hôtes de l'invention.

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