Cell populations which co-express cd49c and cd90

Details Cell populations which co-express cd49c and cd90 Cell populations which co-express cd49c and cd90

C - Chemistry, Metallurgy

12

N

C12N 5/078 (2010.01) C12N 5/071 (2010.01) A61K 35/12 (2006.01) A61K 35/28 (2006.01) A61P 9/00 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2709442

Substantially homogenous cells populations which co-express CD49c, CD90 and telomerase are made. In one embodiment, humans suffering from a degenerative, traumatic, acute injury, cardiac or neurological condition are treated with the substantially homogenous cells populations which co-express CD49c, CD90 and telomerase. In another embodiment, committed progenitor cells are made are made by selecting from a cultured source of a cell populations which co-express CD49c and CD90 and modifying the cell population. The committed progenitor cells can be employed to treat a human suffering from a degenerative, traumatic, acute injury, cardiac or neurological condition and to formulate pharmaceutical compositions. In a further embodiment, a substantially homogenous populaton of cells which co-express CD49c, CD90 and at least one cardiac-related transcription factor is made and can be used to treat a human suffering from a cardiac condition.

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