Cell production

Details Cell production Cell production

C - Chemistry, Metallurgy

12

N

C12N 5/06 (2006.01) C07K 14/47 (2006.01) C12N 5/08 (2006.01) A61K 35/12 (2006.01)

Patent

CA 2397292

A method of producing neurectoderm cells, which method includes providing a source of early primitive ectoderm-like (EPL) cells; a conditioned medium as hereinbefore defined; or an extract therefrom exhibiting neural inducing properties; and contacting the EPL cells with the conditioned medium, for a time sufficient to generate controlled differentiation to neurectoderm cells.

La présente invention concerne un procédé permettant de produire des cellules neurectodermiques, qui consiste à obtenir une source de cellules primitives précoces de type ectodermique (EPL) ; un milieu conditionné tel que défini dans les pièces descriptives de l'invention ; ou un extrait de ce dernier possédant des propriétés d'induction neuronale ; et à mettre les cellules EPL en contact avec le milieu conditionné pendant une durée suffisamment longue pour générer une différenciation contrôlée en cellules neurectodermiques.

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