Cell separation

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/00 (2006.01) C12N 1/02 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2199020

The present invention provides the use of a milk protein to block the non- specific binding of cells to a solid phase selective cell-capture matrix. Generally speaking, the solid phase selective capture matrix will be a solid support adapted for the selective separation of target cells by means of a target-specific binding partner such as an antibody.

La présente invention porte sur l'emploi d'une protéine du lait pour bloquer la fixation aspécifique de cellules à une matrice de capture cellulaire sélective en phase solide. D'une manière générale, la matrice de capture sélective en phase solide sera un support solide se prêtant à la séparation sélective de cellules cibles par l'entremise d'un partenaire de fixation ciblée, un anticorps, par exemple.

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