Cell-support matrix and a method for preparation thereof

Details Cell-support matrix and a method for preparation thereof Cell-support matrix and a method for preparation thereof

A - Human Necessities

61

L

A61L 27/56 (2006.01) A61L 27/24 (2006.01) A61L 27/38 (2006.01) A61L 27/14 (2006.01)

Patent

CA 2623106

A cell-support matrix having narrowly defined uniformly vertically and non- randomly organized porosity and pore density and a method for preparation thereof. The matrix suitable for preparation of cellular or acellular implants for growth and de novo formation of an articular hyaline-like cartilage. A gel- matrix composite system comprising collagen-based matrix having a narrowly defined porosity capable of inducing hyaline- like cartilage production from chondrocytes in vivo and in vitro.

L'invention concerne une matrice support de cellules dont la densité des pores et la porosité sont définies spécifiquement, de manière uniforme verticalement et organisées de manière non aléatoire, et un procédé de préparation de celle-ci. La matrice convient pour la préparation d'implants cellulaires ou acellulaires destinés à stimuler la croissance et la formation de novo d'un cartilage articulaire du type hyaline. Le système composite gel-matrice comprend une matrice à base de collagène dont la porosité, définie spécifiquement, permet d'induire la production in vivo et in vitro de cartilage du type hyaline à partir de chondrocytes.

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