Cell surface antigen associated with cellular apoptosis

C - Chemistry – Metallurgy – 12 – P

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C12P 21/08 (2006.01) A61K 39/395 (2006.01) C07K 14/15 (2006.01) C07K 14/705 (2006.01) C07K 16/10 (2006.01) C07K 16/28 (2006.01) C12N 5/16 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2071205

A 52kD antigen associated with cellular apoptosis is described. The antigen is expressed by activated and malignant lymphoid cells. Antibodies which bind the antigen induce growth inhibition and apoptosis.

On décrit un antigène 52kD associé à l'apoptose cellulaire. L'antigène est exprimé par des cellules lymphoïdes activées et malignes. Les anticorps qui se fixent sur les antigènes provoquent l'inhibition de la croissance cellulaire et l'apoptose.

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