Cell surface antigens of human astrocytoma

C - Chemistry – Metallurgy – 12 – N

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167/37, 195/1.10

C12N 15/00 (2006.01) A61K 39/395 (2006.01) C07K 16/30 (2006.01) G01N 33/577 (2006.01)

Patent

CA 1210346

ABSTRACT Method of forming an antibody producing hybridoma cell line by fusing a myeloma derived cell strain with splenocytes derived from BALB/c mice immunized with human astrocytoma tumor cells, the hybridoma cell line formed, and the monoclonal antibodies generated by said cell line. A method of phenotyping astrocytoma tumor cells comprising determining the reaction of said cells to various phenotyped monoclonal antibodies to astrocytoma tumor cells is also provided.

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