Cell surface display of proteins by recombinant host cells

Details Cell surface display of proteins by recombinant host cells Cell surface display of proteins by recombinant host cells

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) C07K 14/52 (2006.01) C12N 9/16 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2390017

Methods and vectors are described for expressing recombinant proteins on the surface of host cells. These processes and compositions provide the basis for strategies to produce a fusion protein, comprising a membrane anchor that allows extracellular attachment of the fusion protein in a type II orientation.

L'invention concerne des méthodes et des vecteurs destinés à l'expression de protéines recombinantes à la surface de cellules hôtes. Des processus et des compositions constituent la base de techniques destinées à la production d'une protéine hybride, une ancre membranaire permettant une fixation extracellulaire de cette protéine hybride dans une orientation de type II.

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