Cell surface receptor antigen vaccines

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 39/00 (2006.01) A61K 48/00 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2351729

The invention provides compositions and methods directed to cell surface receptor antigen specific vaccines. More specifically, vaccines are provided that induce or enhance host antibody titers specific for cell surface receptor antigens and that include recombinant expression constructs containing nucleic acids encoding a target cell surface receptor antigen and one or more immune response altering molecules, or the expressed products themselves.

cette invention concerne des compositions et des procédés relatifs à des vaccins spécifiques d'antigènes récepteurs de surface cellulaire. Plus précisément, il s'agit de vaccins qui induisent ou améliorent chez l'hôte les titres d'anticorps hôtes d'antigènes récepteurs de surface cellulaire. Ces vaccins comprennent des constructions d'expression recombinante qui renferment des acides nucléiques codant pour un antigène récepteur de surface cellulaire cible et une ou plusieurs molécules modifiant la réponse immunitaire, ou les produits exprimés eux-mêmes.

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