Cells expressing anti-fc receptor binding components

Details Cells expressing anti-fc receptor binding components Cells expressing anti-fc receptor binding components

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 39/00 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) A61P 37/04 (2006.01) C07K 14/71 (2006.01) C07K 16/28 (2006.01) C07K 19/00 (2006.01) C12N 5/10 (2006.01) C12N 5/22 (2006.01) C12N 15/13 (2006.01) C12N 15/85 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2311574

Cells transformed to express on their surface a component which binds to an Fc receptor of an effector cell are disclosed. Also disclosed are expression vectors used to transform the cells. Once transformed, the cells bind to effector cells via the Fc receptor of the effector cell to stimulate an effector cell mediated immune response.

L'invention porte sur des cellules transformées pour exprimer à leur surface un composant se fixant au récepteur Fc d'une cellule effectrice, et sur les vecteurs d'expression servant à transformer lesdites cellules. Une fois transformées, les cellules se fixent aux cellules effectrices par l'intermédiaire du récepteur Fc desdites cellules effectrices pour stimuler une réponse immunitaire induite par les cellules effectrices.

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