C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/0789 (2010.01) C12N 5/078 (2010.01) A61K 35/14 (2006.01) A61K 48/00 (2006.01) A61P 7/00 (2006.01) A61P 37/00 (2006.01) C12N 5/10 (2006.01) C12Q 1/02 (2006.01) G01N 33/50 (2006.01) A61K 35/12 (2006.01)
Patent
CA 2470707
The invention relates to cellular compositions comprising hematopoietic cells with the potential or increased potential to form non-hematopoietic cells; methods for producing such cellular compositions; methods for differentiation of cells of cellular compositions of the invention into cells that exhibit morphological, physiological, functional, and/or immunological features of non- hematopoietic cells; and uses of the cellular compositions. The invention also relates to a method for the expansion of hematopoietic stem and progenitor cells.
L'invention concerne des compositions cellulaires renfermant des cellules hématopoïétiques ayant le potentiel ou un potentiel accru de formation de cellules non hématopoïétiques; des procédés de préparation de telles compositions cellulaires; des procédés de différentiation cellulaire de compositions cellulaires selon l'invention en cellules présentant des caractéristiques morphologiques, physiologiques, fonctionnelles et/ou immunologiques de cellules non hématopoïétiques; et des utilisations des compositions cellulaires. L'invention concerne également un procédé d'expansion de cellules souches hématopoïétiques.
Casper Robert
Rogers Ian
Mccarthy Tetrault Llp
Mount Sinai Hospital
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